Products in development

Genmab is developing a pipeline of antibody therapeutics with eighteen products in clinical development, including two marketed products, and approximately 20 in-house and partnered pre-clinical programs. Our pipeline currently includes naked antibodies, Antibody Drug Conjugates (ADCs), bispecific antibodies created from our DuoBody® technology platform, and antibodies created with our HexaBody® technology.

Product Indication Development Phase
Pre-
clinical
I I/II II III  
Daratumumab
Partner: Janssen Biotech
Multiple myeloma (MM)

III
  Amyloidosis  III
  Natural Killer/T-Cell lymphoma (NKTCL) Nasal Type

 II
Ofatumumab (OMB157) Autoimmune (subcutaneous formulation)
Partner: Novartis
Relapsing multiple sclerosis (RMS) III
Tisotumab vedotin
Partner: Seattle Genetics
Cervical cancer


  II
   Ovarian cancer   II
   Solid tumors
  II 
Enapotamab vedotin (HuMax-AXL-ADC)
Solid tumors
     I/II
HexaBody-DR5/DR5 (GEN1029)
Solid tumors

     I/II
DuoBody-CD3xCD20 (GEN3013)
Hematological malignancies

 
     I/II
DuoBody-PD-L1x4-1BB (GEN1046)
Partner: BioNTech
 Solid tumors        I
DuoBody-CD40x4-1BB (GEN1042)
Partner: BioNTech
Solid tumors
      I
Teprotumumab
Partner: Horizon Pharma
Thyroid eye disease
III
HuMax-IL8
Partner: BMS
Advanced cancers        I/II
Camidanlumab tesirine (ADCT-301)
Partner: ADC Therapeutics
Lymphoma
      I
   Solid tumors       I
JNJ-61186372
Partner: Janssen Biotech
Non-small-cell lung cancer (NSCLC)       I
JNJ-63709178
Partner: Janssen Biotech
Acute myeloid leukemia (AML)      
JNJ-67571244
Partner: Janssen Biotech
AML or MDS        I
JNJ-63898081
Partner: Janssen Biotech
Solid tumors        I
JNJ-64007957
Partner: Janssen Biotech
Relapsed or refractory MM      
JNJ-64407564
Partner: Janssen Biotech
Relapsed or refractory MM      
Lu AF82422
Partner: Lundbeck
Parkinson's disease        I
~20 Active Pre-clinical Programs Partnered & proprietary programs: HuMab, DuoBody, DuoHexaBody & HexaBody


Pre-clinical




Follicular lymphoma (FL)
Follicular lymphoma (FL)
Follicular lymphoma (FL)