Genmab is building a deep pipeline of fully human antibody products to maximize its opportunities for success. We have ten products in clinical trials and have the financial flexibility needed to move our products forward. Genmab has chosen to focus on products to treat various cancers, infectious diseases, and autoimmune and inflammatory conditions. Human antibodies are expected to be particularly useful in treating these conditions as they should lend themselves to long-term therapy without the risk of rejection by the body's immune system. Furthermore, Genmab is evaluating a large number of interesting disease targets, including several concerning infectious diseases, for future product development.
TitleIndicationsDevelopment StatusOur Rights
HuMax-CD4 (zanolimumab)
Cutaneous T-Cell Lymphoma (CTCL)Phase IIIWorldwide
Non-Cutaneous T-Cell Lymphoma (NCTCL)Phase II (completed)Worldwide
NCTCL CombinationPhase IIWorldwide
HuMax-CD20 (ofatumumab)
Chronic Lymphocytic Leukemia (CLL)Phase IIIWorldwide in collaboration with GlaxoSmithKline
Non-Hodgkin’s Lymphoma (NHL)Phase IIIWorldwide in collaboration with GlaxoSmithKline
Rheumatoid Arthritis (RA)Phase IIIWorldwide in collaboration with GlaxoSmithKline
RAPhase IIIWorldwide in collaboration with GlaxoSmithKline
CLL Front LinePhase IIWorldwide in collaboration with GlaxoSmithKline
NHL Front LinePhase IIWorldwide in collaboration with GlaxoSmithKline
Diffuse large B-cell lymphoma (DLBCL)Phase IIWorldwide in collaboration with GlaxoSmithKline
HuMax-EGFr (zalutumumab)
Head and neck cancerPhase IIIWorldwide
Head and neck cancer front linePhase IIIWorldwide
Non small cell lung cancerPhase IIWorldwide
Head and neck cancer front linePhase I/IIWorldwide
AMG 714
Rheumatoid Arthritis (RA)Phase II (completed)Worldwide in collaboration with Amgen
PsoriasisPhase IWorldwide in collaboration with Amgen
R1507
SarcomaPhase IIWorldwide in collaboration with Roche
HuMax-IL8
Palmoplantar pustulosisPhase I/II (completed)Worldwide
HuMax-CD38
Multiple MyelomaPhase I/IIWorldwide
Roche 2
UndisclosedPhase IWorldwide in collaboration with Roche
Roche 3
UndisclosedPhase IWorldwide in collaboration with Roche
Roche 4
AsthmaPhase IWorldwide in collaboration with Roche
HuMax-HepC
Hepatitis CPre-clinicalWorldwide rights acquired from Connex GmbH and INSERM
HuMax-TAC
Organ transplant rejectionPre-clinicalWorldwide
HuMax-CD32b
CancerPre-clinicalWorldwide