MAJOR SHAREHOLDER ANNOUNCEMENT

Copenhagen, Denmark; April 7, 2008 – Genmab A/S (OMX: GEN) announces under reference to Section 29 of the Danish Securities Trading Act that Lucerne Capital Management, LLC (formerly Reach Capital) has informed us that their ownership in Genmab A/S as of April 1, 2008 consists of 1,471,848 shares, which is 3.31% of the total shares in the Company.

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