Press Center » Archived News Releases » 2000
COPENHAGEN, Denmark; April 11, 2000 - Genmab A/S announced
today that it has raised DKK 35,032,500 (approximately $4.8 million) and
added a new anticancer product to its portfolio of human antibodies in
development. With the addition of this new pre-clinical program, Genmab has
four products in development, including one in human clinical trials. In
addition, the Company has acquired unlimited access to the HuMAb-Mouse™
technology through an expanded license from Medarex, Inc. This license gives
Genmab the ability to create an unlimited number of new fully human antibody
products.
"This broad expansion of Genmab's license means the Company has
unlimited potential to expand its portfolio of products," said Lisa N.
Drakeman, Ph.D., Chief Executive Officer of Genmab. "The additional
financing also strengthens the Company and helps us expand our product
development efforts."
Genmab is a biotechnology company developing a portfolio
of fully human antibodies using the proprietary HuMAb-Mouse™ technology. The
Company has one product in Phase I/II clinical trials to treat rheumatoid
arthritis, and three products in pre-clinical development, one for
inflammation and two for cancer. Human antibodies are expected to provide a
treatment advantage over other antibody-based products, especially since
antibodies containing mouse proteins are likely to be rejected by the body
when used over time and can lead to allergic-type reactions. In addition to
these advantages, the HuMAb antibodies often have very high affinities, one
hundred to one thousand times higher than those made in wild type mice. High
affinities should result in better binding to the disease target and
increased effectiveness for the products. Furthermore, fully human antibodies
are likely to have longer half-lives than previous types of antibodies, which
could contribute significantly to their therapeutic effectiveness.
Certain statements in this press release consist of forward-looking
statements that involve risks and uncertainties including, but not limited
to, uncertainties regarding the timing and success of drug development
programs, or the availability of future financing. Actual results, events or
performance may differ materially.
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