Press Center » Archived News Releases » 1999
COPENHAGEN, Denmark; May 17, 1999 - Genmab A/S announced
today that it has obtained exclusive rights to patents to develop antibodies
against IL15, a cytokine implicated in a variety of inflammatory conditions
including arthritis, psoriasis and inflammatory bowel disease. Genmab is
developing a portfolio of fully human antibodies derived from Medarex's
(Nasdaq: MEDX) HuMAb-Mouse™ technology.
These rights were obtained from Immunex Corporation (Nasdaq: IMNX) through a
sub-license from Medarex. Immunex retains an option to commercialize the
resulting fully human IL15 antibody and, in that event would provide a
license fee, milestone payments and profit sharing to Genmab. If Genmab
commercializes the IL15 antibody, it would pay Immunex milestone fees and
royalties. Immunex will also provide scientific and technical assistance to
Genmab with respect to IL15. Immunex has retained its rights to IL15 for
therapeutic and diagnostic purposes.
In a separate transaction not involving Immunex, Genmab has also increased
its capital resources as a result of an additional $2 million investment by
current shareholders, led by BankInvest Biomedical Development Fund. At the
same time, Genmab has received a license to an additional target from
Medarex, in exchange for equity, and will use the additional capital to
expand product development activities.
"A human antibody against IL15 has the potential to treat diseases that
affect millions of people," said Lisa N. Drakeman, Ph.D., Chief
Executive Officer of Genmab. "We look forward to moving this product
into clinical trials."
Immunex is a biopharmaceutical company dedicated to developing immune system
science to protect human health. The company's products offer hope to
patients with cancer, inflammatory and infectious diseases.
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